surmount trials tirzepatide weight loss results SURMOUNT-1 (NEJM 2022) tested tirzepatide — a dual GIP/GLP-1 receptor agonist — in 2,539 adults with obesity and achieved up to 20.9% mean weight loss at the highest dose. 57% of participants
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Those taking GLP-1 medications for diabetes and weight loss often experience gastrointestinal symptoms, but some lesser-known side effects have also been reported.
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