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Role of a Dual Glucose-Dependent Insulinotropic Peptide (GIP)/Glucagon-like Peptide-1 Receptor Agonist (Twincretin) in Glycemic Control: From Pathophysiology to Treatment

9/ The First Drug In April 2005, the FDA approved Byetta (exenatide). The first GLP-1 receptor agonist. By modern standards it was modest. Twice-daily injections. Moderate glucose control. Modest weight loss. But

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